Taking Alpha-Lipoic Acid for 40 days after Carpal Tunnel Surgery can decrease the likelihood of developing Pillar Pain.

Filippo, B., Granchi, D., Roatti, G., Merlini, L., Sabattini, T., & Baldini, N. (2017). Alpha-lipoic acid after median nerve decompression at the carpal tunnel: A randomized controlled trial. The Journal of Hand Surgery, 4, 236–42.

The Skinny – A double-blind, randomized controlled study was performed. Sixty-four patients were randomly assigned into two groups after median nerve decompression. Thirty-two patients took the alpha-lipoic acid (ALA), while the other 32 received the placebo pill. 

alpha lipoic acid carpal tunnel

In The Weeds – The outcome measures utilized were Boston Carpal Tunnel score, 2-point discrimination, presence or absence of pillar pain, use of analgesics beyond post-op day 2, and sensory and motor conduction velocities.   These measures were assessed at three months post-op. 

Bringing it Home –  ALA did not significantly improve nerve conduction velocity or Boston Carpal Tunnel score. Taking ALA did reduce pillar pain, and static 2-point discrimination improved in both groups. 

Taking ALA for 40 days after carpal tunnel surgery can lower the incidence of Pillar Pain.   The study size was relatively small, and the outcome measures of pain and two-point discrimination test are somewhat subjective measures. The ALA treatment (pillar pain treatment) was well tolerated by the study participants. A larger study is needed to confirm these findings. 

Leave a Comment






More To Read

Ways to Improve HEP Compliance  in Hand Therapy 

April 17, 2022

Ways to Improve HEP Compliance  in Hand Therapy  By: Dalton Busch  One of the most important ways we see our patient’s progress is by assuring they are compliant with their prescribed home exercise program (HEP). Our patients are always encouraged to adhere to their prescribed program but compliance is easier said than done. Reminding patients…

Scar Management in Hand Therapy

November 17, 2019

Hand therapists may feel they are in a constant battle with scar tissue. It can limit ROM, cause pain, impede other structures, and leave a less than desirable appearance.  Scar tissue starts forming as early as 2 weeks after an injury and can continue forming for up to 2 years. The earlier action is taken…

Exertional (Chronic) Compartment Syndrome of The Hand

January 11, 2025

By: Tommi Long What is it? Chronic exertional compartment syndrome (CECS) is an exercise-induced condition affecting the muscles and nerves, leading to pain, swelling, and reduced muscle function due to increased pressure and restricted circulation. While most commonly, it impacts the arms and legs, it is rare to happen in the hand(s). CECS is most…

INTEROSSEOUS MUSCLE TIGHTNESS TESTING

June 11, 2022

May 2012 No. 19 INTEROSSEOUS MUSCLE TIGHTNESS TESTING Judy Colditz, OT/L, CHT, FAOTA INTEROSSEOUS MUSCLE TIGHTNESS TESTING – ARE YOU DOING IT CORRECTLY? The common term “Intrinsic Tightness Testing” is a misnomer as it describes a maneuver specifically designed to test tightness of the interosseous muscles. The interosseous muscles are small, short-fibered muscles contained within…

Envelope_1

Sign-up to Get Updates Straight to Your Inbox!

Sign up with us and we will send you regular blog posts on everything hand therapy, notices every time we upload new videos and tutorials, along with handout, protocols, and other useful information.