Taking Alpha-Lipoic Acid for 40 days after Carpal Tunnel Surgery can decrease the likelihood of developing Pillar Pain.

Filippo, B., Granchi, D., Roatti, G., Merlini, L., Sabattini, T., & Baldini, N. (2017). Alpha-lipoic acid after median nerve decompression at the carpal tunnel: A randomized controlled trial. The Journal of Hand Surgery, 4, 236–42.

The Skinny – A double-blind, randomized controlled study was performed. Sixty-four patients were randomly assigned into two groups after median nerve decompression. Thirty-two patients took the alpha-lipoic acid (ALA), while the other 32 received the placebo pill. 

alpha lipoic acid carpal tunnel

In The Weeds – The outcome measures utilized were Boston Carpal Tunnel score, 2-point discrimination, presence or absence of pillar pain, use of analgesics beyond post-op day 2, and sensory and motor conduction velocities.   These measures were assessed at three months post-op. 

Bringing it Home –  ALA did not significantly improve nerve conduction velocity or Boston Carpal Tunnel score. Taking ALA did reduce pillar pain, and static 2-point discrimination improved in both groups. 

Taking ALA for 40 days after carpal tunnel surgery can lower the incidence of Pillar Pain.   The study size was relatively small, and the outcome measures of pain and two-point discrimination test are somewhat subjective measures. The ALA treatment (pillar pain treatment) was well tolerated by the study participants. A larger study is needed to confirm these findings. 

Leave a Comment






More To Read

Hand Therapy: How to Treat the Client with a New Distal Radius Fracture

May 5, 2019

A short blog post on the basics of treating a Distal Radius Fracture.

Occupation Based Interventions in Hand Therapy

September 24, 2022

Keeping Occupation Based Interventions in Hand Therapy By: Tristany Hightower Are your treatments occupation based? Do you tailor your activity choices to fit the needs of each patient? As occupational therapists, we should be specialists in creating goals and interventions that are directed at returning our patients to meaningful occupations.  Too often, hand therapy can…

Which is better: Splinting the MCP or PIP joint when managing Trigger Finger?

June 2, 2019

Teo, S. H., Ng D. C., Wong, Y.K.(2018).  Effectiveness of proximal interphalangeal joint blocking orthosis vs metacarpophalangeal joint blocking orthosis in trigger digit: A randomized clinical trial. Journal of Hand Therapy, 1-7. The Skinny- This study compared PIP joint immobilization via an Oval-8TM with a custom MCP blocking trigger finger orthosis treatment.  In the Weeds…

What is the Effectiveness of IASTM?

September 8, 2019

Citation Kim, J., Sung, D. J., Lee, J. (2017). Therapeutic effectiveness of instrument-assisted soft tissue mobilization for soft tissue injury: Mechanisms and practical application. Journal of Exercise Rehabilitation, 13(1). doi: https://doi.org/10.12965/jer.1732824.412 The skinny IASTM is a relatively simple technique that uses the surface of an instrument to minimize the amount of pressure or force needed…

Envelope_1

Sign-up to Get Updates Straight to Your Inbox!

Sign up with us and we will send you regular blog posts on everything hand therapy, notices every time we upload new videos and tutorials, along with handout, protocols, and other useful information.