Taking Alpha-Lipoic Acid for 40 days after Carpal Tunnel Surgery can decrease the likelihood of developing Pillar Pain.

Filippo, B., Granchi, D., Roatti, G., Merlini, L., Sabattini, T., & Baldini, N. (2017). Alpha-lipoic acid after median nerve decompression at the carpal tunnel: A randomized controlled trial. The Journal of Hand Surgery, 4, 236–42.

The Skinny – A double-blind, randomized controlled study was performed. Sixty-four patients were randomly assigned into two groups after median nerve decompression. Thirty-two patients took the alpha-lipoic acid (ALA), while the other 32 received the placebo pill. 

alpha lipoic acid carpal tunnel

In The Weeds – The outcome measures utilized were Boston Carpal Tunnel score, 2-point discrimination, presence or absence of pillar pain, use of analgesics beyond post-op day 2, and sensory and motor conduction velocities.   These measures were assessed at three months post-op. 

Bringing it Home –  ALA did not significantly improve nerve conduction velocity or Boston Carpal Tunnel score. Taking ALA did reduce pillar pain, and static 2-point discrimination improved in both groups. 

Taking ALA for 40 days after carpal tunnel surgery can lower the incidence of Pillar Pain.   The study size was relatively small, and the outcome measures of pain and two-point discrimination test are somewhat subjective measures. The ALA treatment (pillar pain treatment) was well tolerated by the study participants. A larger study is needed to confirm these findings. 

Leave a Comment






More To Read

Changes in ROM of the MCP after Trapeziometacarpal Arthrodesis 

December 19, 2021

Rapid Review: Changes in ROM of the MCP after Trapeziometacarpal Arthrodesis Hayashi, M., Kato, H., Komatsu, M., Yamazaki, H., Uchiyama, S., & Takahashi, J. (2021). Changes in the Functional Range of Motion of the Thumb Metacarpophalangeal Joint After Trapeziometacarpal Arthrodesis for Patients With Advanced Trapeziometacarpal Osteoarthritis. The Journal of hand surgery, S0363-5023(21)00613-4. Advance online publication. https://doi.org/10.1016/j.jhsa.2021.09.018. The Skinny: Several published…

Hand Pain in Pregnancy and the New Parent

September 27, 2020

By: Rachel Reed The transition to parenting can be difficult on a mother or parent’s body, especially when considering the increase in repetitive hand use required to care for a baby. The most common upper extremity conditions that develop during pregnancy and postpartum are carpal tunnel syndrome and de Quervain’s tenosynovitis (Wagner, 2019). Frequently, new…

Sensory Processing in People With and Without Tendinopathy

December 22, 2024

Emilee Sanders, OTS Sensory Processing in People With and Without Tendinopathy: A Systematic Review With Meta-analysis of Local, Regional, and Remote Sites in Upper- and Lower-Limb Conditions Rio, E, Sandler, J., Cheng, K., Moseley, G. L., Cook, J., & Girdwood, M. (2021) Sensory processing in people with and without tendinopathy: A systematic review with meta-analysis…

Carpal Fractures: A Brief Overview

July 18, 2021

Carpal fractures account for 8% of fractures in the upper extremity.  The carpals are situated between the (distal radius and ulna) and the metacarpals. They make up the proximal row- Scaphoid, Lunate, Triquetrum,  and Pisiform, the distal row- Trapezium, Trapezoid, Capitate, and Hamate.   Here are some of the most common carpal bone fracture Scaphoid…

Envelope_1

Sign-up to Get Updates Straight to Your Inbox!

Sign up with us and we will send you regular blog posts on everything hand therapy, notices every time we upload new videos and tutorials, along with handout, protocols, and other useful information.